TY  - JOUR
PY  - 2019//
TI  - Psychiatric comorbidities in patients with intentional methanol intoxication
JO  - Neuropsychiatric disease and treatment
A1  - Yang, Wei-Sheng
A1  - Yen, Tzung-Hai
A1  - Juang, Yeong-Yuh
A1  - Lee, Shwu-Hua
A1  - Wang, Bi-Hwa
A1  - Lee, Chin-Pang
SP  - 397
EP  - 402
VL  - 15
IS  - 
N2  - BACKGROUND: Intentional methanol intoxication (IMI) is an emerging public health issue in Asian countries, but few data are available in the literature on underlying psychiatric comorbidities in these suicide attempters. <br><br>PATIENTS AND METHODS: We conducted a retrospective chart review on patients with methanol intoxication (MI) treated at Chang-Gung Memorial Hospital, Linkou, Taiwan during 2000-2016. Of the 56 cases of documented MI, 16 were IMI. Baseline demographic, clinical, laboratory, psychiatric diagnoses, and mortality data were collected and analyzed. <br><br>RESULTS: Patient group with IMI had more females (62.5% vs 7.5%, <i>P</i>=0.000), less alcohol consumption (33.3% vs 92.5%, <i>P</i>=0.000), and less smoking (40.0% vs 79.5%, <i>P</i>=0.009), but higher past psychiatric disease (73.3% vs 10.0%, <i>P</i>=0.000) and past suicide attempts (81.1% vs 2.5%, <i>P</i>=0.000) than patient group with unintentional MI (UMI). Pesticides (50.0%) comprised the most common source used for suicide, followed by industrial methanol (37.5%). There was no significant difference in mortality rates between these two group (25.0% vs 22.5%, <i>P</i>=0.548). Twelve (75.0%) survivors of IMI were referred to a psychiatric consultation-liaison team, and depressive disorder (58.3%) and adjustment disorder (25.0%) were common. <br><br>CONCLUSION: There is a female predominance and a high prevalence of psychiatric comorbidities, namely depression and adjustment disorder in patients with IMI. Besides, alcohol consumption is a prevalent but not adequately treated condition in UMI group.<p />  <p>Language: en</p>
LA  - en
SN  - 1176-6328
UR  - http://dx.doi.org/10.2147/NDT.S192943
ID  - ref1
ER  -