TY  - JOUR
PY  - 2019//
TI  - Sleepiness and driving events in shift workers: the impact of circadian and homeostatic factors
JO  - Sleep
A1  - Mulhall, Megan D.
A1  - Sletten, Tracey L.
A1  - Magee, Michelle
A1  - Stone, Julia E.
A1  - Ganesan, Saranea
A1  - Collins, Allison
A1  - Anderson, Clare
A1  - Lockley, Steven W.
A1  - Howard, Mark E.
A1  - Rajaratnam, Shantha M. W.
SP  - ePub
EP  - ePub
VL  - 42
IS  - 6
N2  - We aimed to characterise objective and subjective sleepiness and driving events during short work commutes and examine the impact of circadian and homeostatic factors across different shift types in a shift worker population. Thirty-three nurses were monitored for 2 weeks over day (07:00-15:30), evening (13:00-21:30) and night shifts (21:00-07:30). Sleep was measured via daily sleep logs and wrist actigraphy. Driving logs were completed for each work commute, reporting driving events and a pre-drive Karolinska Sleepiness Scale (KSS). Ocular data from a subset of participants (n=11) assessed objective sleepiness using infrared oculography during commutes. Circadian phase was assessed at 3 time-points via urinary 6-sulphatoxymelatonin (aMT6s) collected over 24-48 hours. Subjective and objective sleepiness and sleep-related and hazardous driving events significantly increased following night shift compared to pre-shift. There were significant shift differences with KSS, sleep-related and inattention-related events highest during the post-night shift commute, compared to day and evening shifts. Sleep-related events were highest following the first night shift, whilst inattention-related events were most frequent after consecutive night shifts. KSS, sleep-related and hazardous events were increased during drives following ≥16h of wakefulness. KSS and sleep-related events increased during drives within ±3h of aMT6s acrophase. An interaction between homeostatic and circadian processes was observed, with KSS and sleep-related events highest within ±3h of acrophase, when wakefulness was ≥16h. In naturalistic conditions subjective and objective sleepiness and driving events are increased following night shifts, even during short (~30 minute) commutes and exacerbated by an interaction between circadian phase and duration of wakefulness.<br><br>© Sleep Research Society 2019. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.<p />  <p>Language: en</p>
LA  - en
SN  - 0161-8105
UR  - http://dx.doi.org/10.1093/sleep/zsz074
ID  - ref1
ER  -