TY  - JOUR
PY  - 2019//
TI  - Detecting sleep apnoea syndrome in primary care with screening questionnaires and the Epworth sleepiness scale
JO  - Medical journal of Australia
A1  - Senaratna, Chamara V.
A1  - Perret, Jennifer L.
A1  - Lowe, Adrian
A1  - Bowatte, Gayan
A1  - Abramson, Michael J.
A1  - Thompson, Bruce
A1  - Lodge, Caroline
A1  - Russell, Melissa
A1  - Hamilton, Garun S.
A1  - Dharmage, Shyamali C.
SP  - 65
EP  - 70
VL  - 211
IS  - 2
N2  - OBJECTIVE: To examine the utility of apnoea screening questionnaires, alone and in combination with the Epworth sleepiness scale (ESS), for detecting obstructive sleep apnoea (OSA) in primary care. DESIGN, SETTING: Prospective validation study in an Australian general population cohort. PARTICIPANTS: 424 of 772 randomly invited Tasmanian Longitudinal Health Study, 6th decade follow-up participants with OSA symptoms (mean age, 52.9 years; SD, 0.9 year) who completed OSA screening questionnaires and underwent type 4 sleep studies. MAIN OUTCOME MEASURES: Clinically relevant OSA, defined as moderate to severe OSA (15 or more oxygen desaturation events/hour), or mild OSA (5-14 events/hour) and excessive daytime sleepiness (ESS ≥ 8); diagnostic test properties of the Berlin (BQ), STOP-Bang and OSA-50 questionnaires, alone or combined with an ESS ≥ 8. <br><br>RESULTS: STOP-Bang and OSA-50 correctly identified most participants with clinically relevant OSA (sensitivity, 81% and 86% respectively), but with poor specificity (36% and 21% respectively); the specificity (59%) and sensitivity of the BQ (65%) were both low. When combined with the criterion ESS ≥ 8, the specificity of each questionnaire was high (94-96%), but sensitivity was low (36-51%). Sensitivity and specificity could be adjusted according to specific needs by varying the STOP-Bang cut-off score when combined with the ESS ≥ 8 criterion. <br><br>CONCLUSIONS: For people likely to trigger OSA assessment in primary care, the STOP-Bang, BQ, and OSA-50 questionnaires, combined with the ESS, can be used to rule in, but not to rule out clinically relevant OSA. Combined use of the STOP-Bang with different cut-off scores and the ESS facilitates a flexible balance between sensitivity and specificity.<br><br>© 2019 AMPCo Pty Ltd.<p />  <p>Language: en</p>
LA  - en
SN  - 0025-729X
UR  - http://dx.doi.org/10.5694/mja2.50145
ID  - ref1
ER  -