TY - JOUR PY - 2019// TI - Tuned to voices and faces: cerebral responses linked to social anxiety JO - NeuroImage A1 - Kreifelts, Benjamin A1 - Eckstein, Kathrin N. A1 - Ethofer, Thomas A1 - Wiegand, Ariane A1 - Wächter, Sarah A1 - Brück, Carolin A1 - Erb, Michael A1 - Lotze, Martin A1 - Wildgruber, Dirk SP - 450 EP - 456 VL - 197 IS - N2 - Voices and faces are the most common sources of threat in social anxiety (SA) where the fear of negative evaluation and social exclusion is the central element. SA itself is spectrally distributed among the general population and its clinical manifestation, termed social anxiety disorder, is one of the most common anxiety disorders. While heightened cerebral responses to angry or contemptuous facial or vocal expressions are well documented, it remains unclear if the brain of socially anxious individuals is generally more sensitive to voices and faces. Using functional magnetic resonance imaging, we investigated how SA affects the cerebral processing of voices and faces as compared to various other stimulus types in a study population with greatly varying SA (N = 50, 26 female). While cerebral voice-sensitivity correlated positive with SA in the left temporal voice area (TVA) and the left amygdala, an association of face-sensitivity and SA was observed in the right fusiform face area (FFA) and the face processing area of the right posterior superior temporal sulcus (pSTSFA). These results demonstrate that the increase of cerebral responses associated with social anxiety is not limited to facial or vocal expressions of social threat but that the respective sensory and emotion processing structures are also generally tuned to voices and faces.

Copyright © 2019. Published by Elsevier Inc.

Language: en

LA - en SN - 1053-8119 UR - http://dx.doi.org/10.1016/j.neuroimage.2019.05.018 ID - ref1 ER -