TY - JOUR PY - 2019// TI - Interaction of childhood trauma with rs1360780 of the FKBP5 gene on trait resilience in a general population sample JO - Journal of psychiatric research A1 - Terock, Jan A1 - Van der Auwera, Sandra A1 - Hannemann, Anke A1 - Janowitz, Deborah A1 - Homuth, Georg A1 - Teumer, Alexander A1 - Grabe, Hans Jörgen SP - 104 EP - 111 VL - 116 IS - N2 -

Highlights • Main and interactive effects of childhood trauma and FKBP5 on resilience were tested in a general-population sample. • Childhood trauma and all subscales were negatively associated with trait resilience. • Rs1360780 showed no main effects on resilience. • Childhood trauma and rs1360780 interacted such that the T-allele enhanced effects of childhood trauma on resilience. • Effects remained stable even after adjusting for depression and PTSD.

Language: en

LA - en SN - 0022-3956 UR - http://dx.doi.org/10.1016/j.jpsychires.2019.06.008 ID - ref1 ER -