Over the past decade, pioneering studies have reported changes in various genes and proteins in postmortem brain samples of major depressive disorder (MDD) patients [e.g., (1–14); see also (15–17)] (Table 1). Even though clear inferences were made based on these results regarding underlying disease mechanisms, the results differ clearly between different studies, often even in opposite directions, and even if the patient groups had been carefully matched for factors like age, sex, and postmortem delay
Language: en
LA - en SN - 0006-3223 UR - http://dx.doi.org/10.1016/j.biopsych.2019.04.015 ID - ref1 ER -