TY - JOUR PY - 2019// TI - Serum cholesterol levels preceding to suicide death in Japanese workers: a nested case-control study JO - Acta neuropsychiatrica A1 - Chen, Sanmei A1 - Mizoue, Tetsuya A1 - Hu, Huanhuan A1 - Kuwahara, Keisuke A1 - Honda, Toru A1 - Yamamoto, Shuichiro A1 - Nakagawa, Tohru A1 - Miyamoto, Toshiaki A1 - Okazaki, Hiroko A1 - Shimizu, Makiko A1 - Murakami, Taizo A1 - Eguchi, Masafumi A1 - Kochi, Takeshi A1 - Yamamoto, Makoto A1 - Ogasawara, Takayuki A1 - Sasaki, Naoko A1 - Uehara, Akihiko A1 - Imai, Teppei A1 - Nishihara, Akiko A1 - Hori, Ai A1 - Nagahama, Satsue A1 - Tomita, Kentaro A1 - Konishi, Maki A1 - Kabe, Isamu A1 - Dohi, Seitaro SP - 1 EP - 13 VL - ePub IS - ePub N2 - OBJECTIVE: To investigate the association between suicide death and serum cholesterol levels as measured at times close to suicide death.

METHODS: We conducted a nested case-control study of 41 cases of suicide deaths and 205 matched controls with serum total cholesterol (TC) levels till three years before suicide death in a large cohort of Japanese workers.

RESULTS: Individuals in the lowest vs. highest tertile/predefined category of TC in a Japanese working population had a three- to four-fold greater risk of suicide death. Each 10 mg/dL decrement of average TC was associated with an 18% increased chance of suicide death (95% confidence interval, 2-35%). Similar results were found for TC levels at each year.

CONCLUSION: These results suggest that a low serum TC level in recent past is associated with an increased risk of suicide death.

Language: en

LA - en SN - 0924-2708 UR - http://dx.doi.org/10.1017/neu.2019.26 ID - ref1 ER -