TY - JOUR
PY - 2019//
TI - Serum cholesterol levels preceding to suicide death in Japanese workers: a nested case-control study
JO - Acta neuropsychiatrica
A1 - Chen, Sanmei
A1 - Mizoue, Tetsuya
A1 - Hu, Huanhuan
A1 - Kuwahara, Keisuke
A1 - Honda, Toru
A1 - Yamamoto, Shuichiro
A1 - Nakagawa, Tohru
A1 - Miyamoto, Toshiaki
A1 - Okazaki, Hiroko
A1 - Shimizu, Makiko
A1 - Murakami, Taizo
A1 - Eguchi, Masafumi
A1 - Kochi, Takeshi
A1 - Yamamoto, Makoto
A1 - Ogasawara, Takayuki
A1 - Sasaki, Naoko
A1 - Uehara, Akihiko
A1 - Imai, Teppei
A1 - Nishihara, Akiko
A1 - Hori, Ai
A1 - Nagahama, Satsue
A1 - Tomita, Kentaro
A1 - Konishi, Maki
A1 - Kabe, Isamu
A1 - Dohi, Seitaro
SP - 1
EP - 13
VL - ePub
IS - ePub
N2 - OBJECTIVE: To investigate the association between suicide death and serum cholesterol levels as measured at times close to suicide death.
METHODS: We conducted a nested case-control study of 41 cases of suicide deaths and 205 matched controls with serum total cholesterol (TC) levels till three years before suicide death in a large cohort of Japanese workers.
RESULTS: Individuals in the lowest vs. highest tertile/predefined category of TC in a Japanese working population had a three- to four-fold greater risk of suicide death. Each 10 mg/dL decrement of average TC was associated with an 18% increased chance of suicide death (95% confidence interval, 2-35%). Similar results were found for TC levels at each year.
CONCLUSION: These results suggest that a low serum TC level in recent past is associated with an increased risk of suicide death.
Language: en
LA - en SN - 0924-2708 UR - http://dx.doi.org/10.1017/neu.2019.26 ID - ref1 ER -