TY  - JOUR
PY  - 2019//
TI  - Risk factors for overdose in young people who received substance use disorder treatment
JO  - American journal on addictions
A1  - Wilens, Timothy E.
A1  - Kelly, John F.
A1  - Bergman, Brandon G.
A1  - Nargiso, Jessica E.
A1  - McKowen, James W.
A1  - Lyons, Rachael M.
A1  - DiSalvo, Maura
A1  - Carrellas, Nicholas W.
A1  - Yule, Amy M.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - BACKGROUND AND OBJECTIVES: To identify substance and psychiatric predictors of overdose (OD) in young people with substance use disorders (SUDs) who received treatment. <br><br>METHODS: We conducted a retrospective review of consecutive medical records of young people who were evaluated in a SUD program between 2012 and 2013 and received treatment. An independent group of patients from the same program who received treatment and had a fatal OD were also included in the sample. OD was defined as substance use associated with a significant impairment in level of consciousness without intention of self-harm, or an ingestion of a substance that was reported as a suicide attempt. t Tests, Pearson's χ<sup>2</sup> , and Fisher's exact tests were performed to identify predictors of OD after receiving treatment. <br><br>RESULTS: After initial evaluation, 127 out of 200 patients followed up for treatment and were included in the sample. Ten (8%) of these patients had a nonfatal OD. Nine patients who received treatment and had a fatal OD were also identified. The sample's mean age was 20.2 ± 2.8 years. Compared with those without OD, those with OD were more likely to have a history of intravenous drug use (odds ratio [OR]: 36.5, P < .001) and mood disorder not otherwise specified (OR: 4.51, P = .01). <br><br>DISCUSSION AND CONCLUSIONS: Intravenous drug use and mood dysregulation increased risk for OD in young people who received SUD treatment. SCIENTIFIC SIGNIFICANCE: It is important to identify clinically relevant risk factors for OD specific to young people in SUD treatment due to the risk for death associated with OD.<br><br>Copyright © 2019 American Academy of Addiction Psychiatry.<p />  <p>Language: en</p>
LA  - en
SN  - 1055-0496
UR  - http://dx.doi.org/10.1111/ajad.12938
ID  - ref1
ER  -