TY  - JOUR
PY  - 2019//
TI  - Prenatal and postnatal exposure to air pollution and emotional and aggressive symptoms in children from 8 European birth cohorts
JO  - Environment international
A1  - Jorcano, Ainhoa
A1  - Lubczyńska, Małgorzata J.
A1  - Pierotti, Livia
A1  - Altug, Hicran
A1  - Ballester, Ferran
A1  - Cesaroni, Giulia
A1  - El Marroun, Hanan
A1  - Fernández-Somoano, Ana
A1  - Freire, Carmen
A1  - Hanke, Wojciech
A1  - Hoek, Gerard
A1  - Ibarluzea, Jesús
A1  - Iñiguez, Carmen
A1  - Jansen, Pauline W.
A1  - Lepeule, Johanna
A1  - Markevych, Iana
A1  - Polańska, Kinga
A1  - Porta, Daniela
A1  - Schikowski, Tamara
A1  - Slama, Rémy
A1  - Standl, Marie
A1  - Tardon, Adonina
A1  - Vrijkotte, Tanja G. M.
A1  - von Berg, Andrea
A1  - Tiemeier, Henning
A1  - Sunyer, Jordi
A1  - Guxens, Mònica
SP  - e104927
EP  - e104927
VL  - 131
IS  - 
N2  - BACKGROUND: The association between air pollution exposure and emotional and behavioural problems in children is unclear. We aimed to assess prenatal and postnatal exposure to several air pollutants and child's depressive and anxiety symptoms, and aggressive symptoms in children of 7-11 years. <br><br>METHODS: We analysed data of 13182 children from 8 European population-based birth cohorts. Concentrations of nitrogen dioxide (NO<sub>2</sub>), nitrogen oxides (NO<sub>x</sub>), particulate matter (PM) with diameters of ≤10 μm (PM<sub>10</sub>), ≤ 2.5 μm (PM<sub>2.5</sub>), and between 10 and 2.5 μm (PM<sub>coarse</sub>), the absorbance of PM<sub>2.5</sub> filters (PM<sub>2.5</sub>abs), and polycyclic aromatic hydrocarbons (PAHs) were estimated at residential addresses of each participant. Depressive and anxiety symptoms and aggressive symptoms were assessed at 7-11 years of age using parent reported tests. Children were classified in borderline/clinical range or clinical range using validated cut offs. Region specific models were adjusted for various socio-economic and lifestyle characteristics and then combined using random effect meta-analysis. Multiple imputation and inverse probability weighting methods were applied to correct for potential attrition bias. <br><br>RESULTS: A total of 1896 (14.4%) children were classified as having depressive and anxiety symptoms in the borderline/clinical range, and 1778 (13.4%) as having aggressive symptoms in the borderline/clinical range. Overall, 1108 (8.4%) and 870 (6.6%) children were classified as having depressive and anxiety symptoms, and aggressive symptoms in the clinical range, respectively. Prenatal exposure to air pollution was not associated with depressive and anxiety symptoms in the borderline/clinical range (e.g. OR 1.02 [95%CI 0.95 to 1.10] per 10 μg/m<sup>3</sup> higher NO<sub>2</sub>) nor with aggressive symptoms in the borderline/clinical range (e.g. OR 1.04 [95%CI 0.96 to 1.12] per 10 μg/m<sup>3</sup> higher NO<sub>2</sub>). Similar results were observed for the symptoms in the clinical range, and for postnatal exposures to air pollution. <br><br>CONCLUSIONS: Overall, our results suggest that prenatal and postnatal exposure to air pollution is not associated with depressive and anxiety symptoms or aggressive symptoms in children of 7 to 11 years old.<br><br>Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0160-4120
UR  - http://dx.doi.org/10.1016/j.envint.2019.104927
ID  - ref1
ER  -