TY  - JOUR
PY  - 2019//
TI  - Outbreak of electronic-cigarette-associated acute lipoid pneumonia - North Carolina, July-August 2019
JO  - MMWR: Morbidity and mortality weekly report
A1  - Fox, Daniel
A1  - Wininger, Jeremy
A1  - Underhill, Bailey
A1  - Rajagopalan, Shrinivas
A1  - Nario, Myra
A1  - Matheis, Edward
A1  - Mansour, Wissam
A1  - Heetderks, Peter
A1  - Brancato, Alison
A1  - Davidson, Kevin
SP  - 784
EP  - 786
VL  - 68
IS  - 36
N2  - Electronic cigarettes (e-cigarettes) produce an aerosol by heating a liquid that usually contains nicotine, flavorings, and other chemicals that users inhale, a behavior commonly referred to as "vaping." E-cigarettes can also be used to deliver marijuana and other drugs. In recent months, more than 200 possible cases of acute lung injury potentially associated with vaping were reported from 25 states (1). During July and August 2019, five patients were identified at two hospitals in North Carolina with acute lung injury potentially associated with e-cigarette use. Patients were adults aged 18-35 years and all experienced several days of worsening dyspnea, nausea, vomiting, abdominal discomfort and fever. All patients demonstrated tachypnea with increased work of breathing on examination, hypoxemia (pulse oximetry <90% on room air), and bilateral lung infiltrates on chest x-ray. All five patients shared a history of recent use of marijuana oils or concentrates in e-cigarettes. All of the products used were electronic vaping pens/e-cigarettes that had refillable chambers or interchangeable cartridges with tetrahydrocannabinol (THC) vaping concentrates or oils, which were all purchased on the street. Three of the patients also used nicotine-containing e-cigarettes, and two of the patients smoked marijuana or conventional cigarettes, although none used other illicit drugs. All five patients were hospitalized for hypoxemic respiratory failure; three required intensive care for acute respiratory distress syndrome, one of whom required intubation and mechanical ventilation. All of the patients survived.<p />  <p>Language: en</p>
LA  - en
SN  - 0149-2195
UR  - http://dx.doi.org/10.15585/mmwr.mm6836e1
ID  - ref1
ER  -