TY  - JOUR
PY  - 2019//
TI  - A case report of acute renal failure caused by Amanita neoovoidea poisoning in Anhui Province, eastern China
JO  - Toxicon: Journal of the International Society on Toxinology
A1  - Wang, Hong
A1  - Wang, Yan
A1  - Shi, Fei-Fan
A1  - Zhang, Shuo
A1  - Fang, Wei-Ting
A1  - Qi, La-Mei
A1  - Wang, Nan
A1  - Huang, Can
A1  - Fang, Hai-Qin
A1  - Li, Hai-Jiao
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Amanita neoovoidea (genus Amanita Pers.) poisoning leads to acute renal failure. Here, we present seven case reports of acute renal failure with acute hepatic failure due to ingestion of A. neoovoidea. Clinical manifestations included gastrointestinal symptoms 1-72 h after ingestion; elevation of renal parameters and blood uric acid, blood urea nitrogen, and creatinine levels; a few abnormal hepatic parameters, primarily albumin decrease and alanine aminotransferase increase; and elevation of zymogram parameters such as cholinesterase and lactate dehydrogenase. To determine whether the hepatic/renal lesions were caused by amanitins, we analyzed the blood and urine samples of patients and specimens of poisonous mushrooms. Morphological and molecular biological analyses indicated that the mushroom was A. neoovoidea. However, no amatoxins and phallotoxins were detected in its basidiomata.<br><br>Copyright © 2019. Published by Elsevier Ltd.<p />  <p>Language: en</p>
LA  - en
SN  - 0041-0101
UR  - http://dx.doi.org/10.1016/j.toxicon.2019.11.007
ID  - ref1
ER  -