TY - JOUR PY - 2019// TI - Renal outcomes among snake-envenomed patients with acute kidney injury in southern India JO - National medical journal of India, The A1 - George, Tarun K. A1 - Toms, Anet Gregory A1 - Fenn, Baker Ninan A1 - Kumar, Vignesh A1 - Kavitha, R. A1 - Georgy, Josh Thomas A1 - Abraham, Georgi A1 - Zachariah, Anand SP - 5 EP - 8 VL - 32 IS - 1 N2 - BACKGROUND:. Acute kidney injury (AKI) is a common complication of snake envenomation. However, the long-term renal outcomes of such patients are not well defined. We aimed to determine the proportion of patients who developed AKI, characterize the presenting syndromes and ascertain the long-term resolution of AKI.

METHODS:. We did a cohort study with prospective follow- up from two centres in southern India. All admitted patients >15 years of age with snake envenomation and serum creatinine ≥1.5 mg/dl over the past 10 years were identified through their discharge summaries. These patients were prospectively contacted, interviewed telephonically and requested to come for a hospital review.

RESULTS:. Of the 866 patients screened, 1 84 developed AKI (21.2%). Among these, 53% had combined renal, haematological and neurological manifestations; 33.6% required admission to the intensive care unit and 38% were dialysed. On follow-up of hospital records the creatinine of 49% of patients had normalized. Of those admitted, 36% were contacted and none had a known renal disease or were on dialysis. Among these, 16 patients came to the hospital for review and only 2 had an elevated creatinine. The total mortality was 1 4.

CONCLUSION:. AKI is an important cause of morbidity with snake envenomation and a proportion will require dialysis. The mortality in our study was low and long-term renal outcomes were relatively good.

Language: en

LA - en SN - 0970-258X UR - http://dx.doi.org/10.4103/0970-258X.272106 ID - ref1 ER -