TY - JOUR PY - 2020// TI - Sensitivity to experiencing alcohol hangovers: reconsideration of the 0.11% blood alcohol concentration (BAC) threshold for having a hangover JO - Journal of clinical medicine A1 - Verster, Joris C. A1 - Kruisselbrink, L. Darren A1 - Slot, Karin A. A1 - Anogeianaki, Aikaterini A1 - Adams, Sally A1 - Alford, Chris A1 - Arnoldy, Lizanne A1 - Ayre, Elisabeth A1 - Balikji, Stephanie A1 - Benson, Sarah A1 - Bruce, Gillian A1 - Devenney, Lydia E. A1 - Frone, Michael R. A1 - Gunn, Craig A1 - Heffernan, Thomas A1 - Hensel, Kai O. A1 - Hogewoning, Anna A1 - Johnson, Sean J. A1 - van Lawick van Pabst, Albertine E. A1 - van de Loo, Aurora J. A. E. A1 - Mackus, Marlou A1 - Merlo, Agnese A1 - Murphy, René J. L. A1 - Owen, Lauren A1 - Palmer, Emily O. C. A1 - van Rossum, Charmaine J. I. A1 - Scholey, Andrew A1 - Terpstra, Chantal A1 - Vatsalya, Vatsalya A1 - Vermeulen, Sterre A. A1 - van Wijk, Michelle A1 - Stock, Ann-Kathrin SP - e179 EP - e179 VL - 9 IS - 1 N2 - The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their "normal" drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their "regular" drinking level, considerably higher alcohol intake-irrespective of the absolute amount-may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned.

Language: en

LA - en SN - 2077-0383 UR - http://dx.doi.org/10.3390/jcm9010179 ID - ref1 ER -