TY  - JOUR
PY  - 2020//
TI  - An adult case of generalized convulsions caused by the ingestion of Ginkgo biloba seeds with alcohol
JO  - Internal medicine
A1  - Azuma, Fumika
A1  - Nokura, Kazuya
A1  - Kako, Tetsuharu
A1  - Kobayashi, Daisuke
A1  - Yoshimura, Teruki
A1  - Wada, Keiji
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - A 64-year-old woman developed symptoms of vomiting and tonic-clonic convulsions 9.5 h after eating 50 roasted Ginkgo biloba seeds with 100 g of alcohol. The intravenous administration of pyridoxal phosphate effectively improved the symptoms. Blood samples were collected and stored over 35 h. The assessment of 4'-O-methylpyridoxine and vitamin B6 vitamers indicated high levels of both, but the pyridoxal phosphate levels were low during the acute stage. These results suggest that 4'-O-methylpyridoxine inhibits the transformation of vitamin B6 analogues to the active form, pyridoxal phosphate. In our case, alcohol may have extended the period until ginkgo intoxication appeared.<p />  <p>Language: en</p>
LA  - en
SN  - 0918-2918
UR  - http://dx.doi.org/10.2169/internalmedicine.4196-19
ID  - ref1
ER  -