TY  - JOUR
PY  - 2020//
TI  - Incidence and risk factors for suicide death among Kaposi's sarcoma patients: a surveillance, epidemiology, and end results analysis
JO  - Medical science monitor
A1  - Shen, Jian
A1  - Zhu, Mingjian
A1  - Li, Sihao
A1  - Wang, Qiangqiang
A1  - Wu, Jingjing
A1  - Li, Yating
A1  - Wang, Qing
A1  - Bian, Xiaoyuan
A1  - Yang, Liya
A1  - Jiang, Xianwan
A1  - Xie, Jiaojiao
A1  - Lu, Yanmeng
A1  - Wang, Kaiceng
A1  - Li, LanJuan
SP  - e920711
EP  - e920711
VL  - 26
IS  - 
N2  - BACKGROUND The suicide risk of patients with cancer is higher than the general population. Our research aimed to explore the Surveillance, Epidemiology, and End Results (SEER) database to define incidence and quest risk factors for death of suicide in patients with Kaposi's sarcoma (KS) in the United States (US). MATERIAL AND METHODS We screened KS patients without human immunodeficiency virus status in the SEER database from 1980 to 2016, calculated the standardized mortality ratios of them by comparing the rates with those of the US general population from 1980 to 2016, and identified relevant suicide risk factors by univariable and multivariable logistic regression analyses. <br><br>RESULTS The suicide rates of KS patients and US general population were 115.31 (110 suicides among 21 405 patients) and 15.1 per 100 000 person-years, respectively, thus the standardized mortality ratio was 7.64 (95% confidence interval [CI], 6.28-9.21). The multivariate analysis showed that black race (versus white race, hazard ratio [HR]: 0.43, 95% CI: 0.21-0.89, P=0.022), advanced age at diagnosis (≥55 years versus 18-44 years, HR: 0.31, 95% CI: 0.14-0.66, P=0.002), and chemotherapy (versus no chemotherapy, HR: 0.60, 95% CI: 0.37-0.96, P=0.032) were protective factors for suicide among KS patients. <br><br>CONCLUSIONS Clinicians and caregivers can apply our findings to identify KS patients with high suicide risk characteristics (white race, age of 18-44 years, non-chemotherapy) and exert timely interventions during patient diagnosis, treatment, and follow-up to reduce the suicide rate in this population.<p />  <p>Language: en</p>
LA  - en
SN  - 1234-1010
UR  - http://dx.doi.org/10.12659/MSM.920711
ID  - ref1
ER  -