TY  - JOUR
PY  - 2020//
TI  - Ammonium dichromate poisoning
JO  - Indian journal of pediatrics
A1  - Kumar, Himanshu
A1  - Kumar, Chandrakanta
A1  - Parmar, Kanak
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Chromium (Cr) is a strong oxidant and poisoning usually begins with gastrointestinal symptoms progressing to multiorgan failure. Lethal dose of chromium salt varies between 6 to 8 g in adults [1, 2] and 1 g in children. In the human body, Cr VI is reduced to Cr III, a non-toxic form, in the plasma but when the reducing capacity is saturated, Cr VI enters the cell and causes damage by lipid peroxidation and enzyme inhibition [3].     Shortly after oral ingestion of chromates gastrointestinal mucosa is damaged, manifesting as rice-water stools, emesis, and corrosive burns of the mouth and esophagus [3]. Systemic absorption in large doses, lead to shock with multiorgan failure especially hepato-renal involvement [4, 5].<p />  <p>Language: en</p>
LA  - en
SN  - 0019-5456
UR  - http://dx.doi.org/10.1007/s12098-020-03331-x
ID  - ref1
ER  -