TY - JOUR PY - 2020// TI - Efficacy of lifestyle and psychosocial interventions in reducing cognitive decline in older people: systematic review JO - Ageing research reviews A1 - Whitty, Emma A1 - Mansour, Hassan A1 - Aguirre, Elisa A1 - Palomo, Marina A1 - Charlesworth, Georgina A1 - Ramjee, Serena A1 - Poppe, Michaela A1 - Brodaty, Henry A1 - Kales, Helen C. A1 - Morgan-Trimmer, Sarah A1 - Nyman, Samuel A1 - Lang, Iain A1 - Walters, Kate A1 - Petersen, Irene A1 - Wenborn, Jennifer A1 - Minihane, Anne-Marie A1 - Ritchie, Karen A1 - Huntley, Jonathan A1 - Walker, Zuzana A1 - Cooper, Claudia SP - ePub EP - ePub VL - ePub IS - ePub N2 - It is unclear what non-pharmacological interventions to prevent cognitive decline should comprise. We systematically reviewed lifestyle and psychosocial interventions that aimed to reduce cognitive decline in healthy people aged 50+, and people of any age with Subjective Cognitive Decline or Mild Cognitive Impairment. We narratively synthesised evidence, prioritising results from studies rated as at lower Risk of Bias (ROB) and assigning Centre for Evidence Based Medicine grades. We included 64 papers, describing: psychosocial (n = 12), multi-domain (n = 10), exercise (n = 36), and dietary (n = 6) interventions. We found Grade A evidence that over 4+ months: aerobic exercise twice weekly had a moderate effect on global cognition in people with/ without MCI; and interventions that integrate cognitive and motor challenges (e.g. dance, dumb bell training) had small to moderate effects on memory or global cognition in people with MCI. We found Grade B evidence that 4+ months of creative art or story-telling groups in people with MCI; 6 months of resistance training in people with MCI and a two-year, dietary, exercise, cognitive training and social intervention in people with or without MCI had small, positive effects on global cognition. Effects for some intervention remained up to a year beyond facilitated sessions.

Language: en

LA - en SN - 1568-1637 UR - http://dx.doi.org/10.1016/j.arr.2020.101113 ID - ref1 ER -