TY  - JOUR
PY  - 2020//
TI  - Identification of a new M-ALPHA analog and MDMA in an illegal health product
JO  - Forensic science international
A1  - Lee, Ji Hyun
A1  - Park, Ok Rim
A1  - Mandava, Suresh
A1  - Kim, Jemin
A1  - Koo, Jaun
A1  - Lee, Jongkook
A1  - Kang, Hoil
SP  - e110332
EP  - e110332
VL  - 313
IS  - 
N2  - The widespread abuse of illicit psychoactive substances is one of the most serious public health and social problems. A suspicious airmail package was seized by Korean customs, and two psychoactive substances in the grayish-green pills in the package were detected by ultra-performance liquid chromatography. The structures of the two substances were elucidated by a combination of liquid chromatography quadrupole time-of-flight mass spectrometry, nuclear magnetic resonance spectroscopy, and comparison with reported or newly generated spectral data of the suggested structures. One of the psychoactive substances proved to be MDMA (commonly known as "Ecstasy"), and the other compound was an M-ALPHA analog bearing a hydroxyl group and an N-methylcarboxamide group. The new M-ALPHA analog was determined as 3-(benzo[d][1,3]dioxol-5-yl)-2-hydroxy-N,2-dimethyl-3-(methylamino)propanamide and named as M-ALPHA-HMCA, wherein HMCA denotes hydroxymethylcarboxamide. Although psychoactivity of this compound has not been assessed, M-ALPHA-HMCA should be considered a potential new psychoactive substance and/or a by-product of MDMA.<p />  <p>Language: en</p>
LA  - en
SN  - 0379-0738
UR  - http://dx.doi.org/10.1016/j.forsciint.2020.110332
ID  - ref1
ER  -