TY  - JOUR
PY  - 2019//
TI  - Interpretation of subgroup analyses in systematic reviews: a tutorial
JO  - Clinical epidemiology and global health
A1  - Richardson, Marty
A1  - Garner, Paul
A1  - Donegan, Sarah
SP  - 192
EP  - 198
VL  - 7
IS  - 2
N2  - Authors of systematic reviews may perform subgroup analyses to investigate how treatment effect varies across different subgroups of patients or trials. Previous research has shown that Cochrane review authors do not sufficiently report their interpretation of subgroup analyses. Consequently, we developed a tutorial with the aim of improving the interpretation of subgroup analyses in reviews. We explain the importance of interpreting subgroup analyses, and demonstrate how to interpret subgroup analyses using theoretical examples and a real-life subgroup analysis with clinical context. Finally, we provide recommendations for the interpretation of subgroup analyses in systematic reviews.<p />  <p>Language: en</p>
LA  - en
SN  - 2452-0918
UR  - http://dx.doi.org/10.1016/j.cegh.2018.05.005
ID  - ref1
ER  -