TY - JOUR PY - 2020// TI - Opioid poisoning JO - Medicine (Abingdon) A1 - Layne, Kerry A1 - Wood, David M. SP - 211 EP - 213 VL - 48 IS - 3 N2 - Opioids are among the most commonly prescribed analgesic medications, and opioid toxicity is becoming an increasing problem across the world. Patients typically present with a triad of signs: reduced consciousness, miosis and a reduced respiratory rate with shallow breaths. Patients with significant opioid toxicity are at risk of airway compromise, and basic supportive measures should be performed. Naloxone is a non-selective μ-opioid receptor antagonist that competitively binds to the μ-opioid receptor and should be administered, ideally intravenously, to patients with significant opioid toxicity.
Language: en
LA - en SN - 1357-3039 UR - http://dx.doi.org/10.1016/j.mpmed.2019.12.018 ID - ref1 ER -