TY  - JOUR
PY  - 2020//
TI  - Alcohols and glycols poisoning
JO  - Medicine (Abingdon)
A1  - Waring, William Stephen
SP  - 185
EP  - 188
VL  - 48
IS  - 3
N2  - Ethanol intoxication is widely encountered and can cause coma, hypotension, hypoglycaemia and acid-base disturbances. Isopropyl alcohol and its metabolite acetone cause profound depression of the central nervous system with rapid onset. Toxic alcohols include methanol, ethylene glycol and diethylene glycol; these cause severe metabolic acidosis, acute renal failure and, for methanol, severe visual disturbance. Toxicity is attributable to metabolites rather than the alcohol or glycol, and there is a characteristic delay between ingestion and severe toxicity. Management strategies include early administration of fomepizole, to minimize formation of toxic metabolites, and haemodialysis to remove metabolites in patients presenting late.<p />  <p>Language: en</p>
LA  - en
SN  - 1357-3039
UR  - http://dx.doi.org/10.1016/j.mpmed.2019.12.009
ID  - ref1
ER  -