TY  - JOUR
PY  - 2020//
TI  - Pathophysiologic mechanisms of concussion, development of chronic traumatic encephalopathy, and emerging diagnostics: a narrative review
JO  - Journal of the American Osteopathic Association
A1  - Berry, James A. D.
A1  - Elia, Christopher
A1  - Sweiss, Raed
A1  - Lawandy, Shokry
A1  - Bowen, Ira
A1  - Zampella, Bailey
A1  - Saini, Harneel
A1  - Brazdzionis, James
A1  - Miulli, Dan
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Pathophysiological mechanisms and cascades take place after a mild traumatic brain injury (mTBI) that can cause long-term sequelae, including chronic traumatic encephalopathy in patients with multiple concurrent TBIs. As diagnostic imaging has become more advanced, microanatomical changes present after mTBI may now be more readily visible. In this narrative review, the authors discuss emerging diagnostics and findings in mTBI through advanced imaging, electroencephalograms, neurophysiologic processes, Q2 biochemical markers, and clinical tissue tests in an effort to help osteopathic physicians to understand, diagnose, and manage the pathophysiology behind mTBI, which is increasingly prevalent in the United States.<p />  <p>Language: en</p>
LA  - en
SN  - 0098-6151
UR  - http://dx.doi.org/10.7556/jaoa.2020.074
ID  - ref1
ER  -