TY - JOUR
PY - 2020//
TI - The history of multiple adverse childhood experiences in patients with schizophrenia is associated with more severe symptomatology and suicidal behavior with gender-specific characteristics
JO - Psychiatry research
A1 - Prokopez, Cintia R.
A1 - Vallejos, Miguel
A1 - Farinola, Romina
A1 - Alberio, Germán
A1 - Caporusso, Gabriela B.
A1 - Cozzarin, Linda G.
A1 - Chiapella, Luciana C.
A1 - Fuentes, Pamela
A1 - Daray, Federico M.
SP - e113411
EP - e113411
VL - 293
IS -
N2 - The current study aims to compare the prevalence of adverse childhood experiences (ACEs) between patients with schizophrenia and non-psychiatric control group, and to analyze the association of having suffered multiple ACEs with clinical symptoms of schizophrenia and suicidal behavior. A multicenter, cross-sectional study was conducted across three facilities in Buenos Aires, Argentina. One-hundred patients with schizophrenia and 50 healthy subjects were assessed with the Adverse Childhood Experiences questionnaire (ACE-Q), the Positive and Negative Syndrome Scale (PANSS), and the Columbia-Suicide Severity Rating Scale (C-SSRS). We observed that the prevalence of at least one ACE in schizophrenic patients was almost double in comparison with the non-psychiatric control group. Multiple ACEs were associated with persistent auditory hallucinations and lower negative symptoms in both sexes. Higher frequency of death ideation and a higher number of suicide attempts were reported among women. The strength of this study is the possibility of comparing the presence of ACEs between schizophrenic patients and non-psychiatric control using the same questionnaire in an under-reported sample of low socio-economic patients assisted in public hospitals. A limitation is that the history of ACEs relied on the retrospective assessment of childhood experiences, and adults could over-report ACEs because of recall bias. Language: en
LA - en
SN - 0165-1781
UR - http://dx.doi.org/10.1016/j.psychres.2020.113411
ID - ref1
ER -