TY  - JOUR
PY  - 2019//
TI  - Age estimation for scald injury and its probable relation to testicular function impairment
JO  - Egyptian journal of forensic sciences and applied toxicology
A1  - Ibrahim, Nermien Attia
A1  - Abdallah, Eman Abdallah
A1  - Kandeel, Nadra Ali
SP  - 87
EP  - 100
VL  - 19
IS  - 2
N2  - Background and Rationale: From the medicolegal point of view, long term systemic consequences of scald injury should be identified for proper compensation and legal action, especially for scald injury involving skin full-thickness in 20% of total body surface area (TBSA) which is known to have long term grave consequences on general health. <br><br>AIM OF THE STUDY: The current experimental study was carried out to: 1-identify the histopathological changes and TNF-α Immunoexpression of different ages of a full thickness scald injury occupying 20% of the total body TBSA; 2- study the probable relation between the scald age and the testicular function impairment. <br><br>MATERIALS AND METHODS: A total number of 40 adult male albino rats were used in the study. Histopathological examination for the scald area and testis were performed with hematoxyline & eosin stain and TNF-α Immunoexpression. Epididymal semen analysis and serum testosterone were also performed. These procedures were carried out after 2 days, 7 days, 1 month and 3 months of scald infliction. <br><br>RESULTS: Progressive histopathological changes were observed in the early scald ages while healing manifestations and improvement in testosterone serum levels, when compared to the other periods, started to appear after 1 and 3 months of scald infliction. <br><br>CONCLUSION: It can be concluded that scald injury involving 20% of TBSA can cause long term impairment of testicular function.<p />  <p>Language: en</p>
LA  - en
SN  - 1687-0875
UR  - http://dx.doi.org/10.21608/ejfsat.2019.6966.1043
ID  - ref1
ER  -