TY - JOUR PY - 2020// TI - Delayed antivenom for life-threatening tiger snake bite: lessons learnt JO - Anaesthesia and intensive care A1 - Tibballs, James A1 - Padula, Andrew M. A1 - Winkel, Kenneth D. A1 - Jackson, Hamish D. SP - ePub EP - ePub VL - ePub IS - ePub N2 - An adolescent victim of an urban snakebite developed respiratory failure, rhabdomyolysis and consumption procoagulopathy but recovered with two vials of tiger snake antivenom administered after a delay of 48 hours. The clinical significance of a post-bite collapse was not initially appreciated. Tiger snake (Notechis spp.) venom antigen was measurable in blood before antivenom but not after whereas antivenom was measurable in blood for nine ensuing days. This case adds to growing evidence that further pharmacokinetic research of venom-antivenom interaction is required to establish the correct dose and timing of tiger snake antivenom. Antivenom therapy, even when delayed, facilitates recovery from snake envenomation.
Language: en
LA - en SN - 0310-057X UR - http://dx.doi.org/10.1177/0310057X20946047 ID - ref1 ER -