TY  - JOUR
PY  - 2020//
TI  - The association between caustic ingestion and psychiatric comorbidity based on 396 adults within 20 years
JO  - Risk management and healthcare policy
A1  - Chen, Yu-Jhou
A1  - Seak, Chen-June
A1  - Chen, Chien-Cheng
A1  - Chen, Tsung-Hsing
A1  - Kang, Shih-Ching
A1  - Ng, Chip-Jin
A1  - Lee, Chao-Wei
A1  - Su, Ming-Yao
A1  - Huang, Hsin-Chih
A1  - Ooyang, Chun-Hsiang
A1  - Hsieh, Sen-Yung
A1  - Cheng, Hao-Tsai
SP  - 1815
EP  - 1824
VL  - 13
IS  - 
N2  - PURPOSE: High prevalence of psychiatric comorbidities (PCs) has been widely documented in caustic substance ingestion cases. However, their effect on the clinical features and prognostic outcomes remains unclear due to the paucity of discussion. We report on detailed clinical courses with long-term multifaceted outcomes and review the association between caustic ingestion and each specific PC.     Patients and Methods: The retrospective chart review included 396 adults (median follow-up, 16.6 months) with and 377 without (control group) PCs treated between 1999 and 2018 at Chang Gung Memorial Hospital. All PCs were diagnosed/confirmed by psychiatrists through face-to-face interviews.     Results: The PCs predicted serious esophagogastroduodenoscopy grading, higher rates of admission/surgery/intensive care unit stay, increments of systemic/gastrointestinal complications, and poorer 5-year overall survival rates. The poor survival among patients with PCs was highly consistent with their baseline characteristics. Significantly advanced age, more non-PCs, alcoholism, illicit drug abuse, and baseline unhealthy status resulted in statistically higher risks of severe complications and limited recovery.     Conclusion: PCs changed clinical patterns and had critical roles in the survival outcomes of caustic injury victims. Clinical awareness achieves benefit by limiting injuries in mild cases or allowing emergent interventions in severe cases. Future studies based on worldwide populations are essential for realizing geographic differences.<p />  <p>Language: en</p>
LA  - en
SN  - 1179-1594
UR  - http://dx.doi.org/10.2147/RMHP.S272527
ID  - ref1
ER  -