TY - JOUR PY - 2020// TI - The pupillary light reflex as a point-of-care test for suicide risk: preliminary results JO - Psychiatry research A1 - McCall, William V. A1 - Sareddy, Sneha A1 - Youssef, Nagy A. A1 - Miller, Brian J. A1 - Rosenquist, Peter B. SP - ePub EP - ePub VL - ePub IS - ePub N2 - The pupillary light reflex (PLR) reflects physiologic arousal, and a potential point-of-care biomarker of suicide risk. We collected data from 9 healthy controls, 6 non-suicidal depressed patients, 7 with prior suicide attempts but not presently suicidal, and 8 depressed patients who were actively suicidal. The pupillary maximum constriction velocity (MCV) was similar between the non-suicidal depressed patients and healthy controls (the "Never suicidal" group). Patients with prior attempt resembled the patients expressing active suicidal ideation (the "Ever suicidal" group). MCV was a significant predictor within a logistic regression model of participants who were "Ever suicidal" versus "Never suicidal".

Language: en

LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2020.113582 ID - ref1 ER -