TY  - JOUR
PY  - 2020//
TI  - Risk factors and prognosis of pediatric open globe injuries without initial light perception
JO  - Ophthalmologica
A1  - Wen, Xin
A1  - Yuan, Miner
A1  - Li, Cheng
A1  - Long, Chongde
A1  - Yuan, Zhaohui
A1  - Zeng, Jieting
A1  - Lin, Xiaofeng
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - PURPOSE: To investigate the possible risk factors and prognosis of initial no light perception (NLP) in pediatric open globe injuries (POGI).     PROCEDURES: This retrospective, comparative, interventional case-control study included 865 eyes of POGI patients presenting to a tertiary referral ophthalmic center from 1 January 2011 to 31 December 2015. Eyes were divided into two groups: NLP group included eyes with initial NLP, and light perception(LP) group included eyes with initial LP or vision better than LP.     RESULTS: The following risk factors were significantly related to initial NLP: severe intraocular hemorrhage (OR=3.287, p=0.015), retinal detachment (RD) (OR=2.527, p=0.007), choroidal damage (OR=2.680, p=0.016) and endophthalmitis (OR=4.221, p＜0.001). Choroidal damage is related to remaining NLP after vitreoretinal surgery (OR=12.384, p=0.003). At the last visit, more eyes in the NLP group suffered from silicone oil-sustained status (OR=0.266, p=0.020) or ocular atrophy (OR=0.640, p=0.004), and less eyes benefitted from final LP (OR=41.061, p＜0.001) and anatomic success (OR=4.515, p＜0.001).     CONCLUSION: Severe intraocular hemorrhage, RD, choroidal damage and endophthalmitis occurred more often in POGI with initial NLP. Choroidal damage was the major factor related to an NLP prognosis. Traumatized eyes with initial NLP could be anatomically and functionally preserved by vitreoretinal surgery.<p />  <p>Language: en</p>
LA  - en
SN  - 0030-3755
UR  - http://dx.doi.org/10.1159/000513337
ID  - ref1
ER  -