TY  - JOUR
PY  - 2020//
TI  - Risk factors for falling for people with multiple sclerosis identified in a prospective cohort study
JO  - Clinical rehabilitation
A1  - Quinn, Gillian
A1  - Comber, Laura
A1  - McGuigan, Chris
A1  - Hannigan, Ailish
A1  - Galvin, Rose
A1  - Coote, Susan
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - OBJECTIVE: To identify risk factors for falling for people with Multiple Sclerosis.     DESIGN: Prospective cohort study.     SETTING: Neurology service in a tertiary hospital.     SUBJECTS: Participants were 101 people with Multiple Sclerosis and Expanded Disability Status Score of 3-6.5. One participant withdrew after the baseline assessment; data were analysed for 100 participants.     INTERVENTIONS: No intervention.     MAIN MEASURES: Outcome was rate of falls, and predictors were Timed Up and Go, Symbol Digit Modalities test, demographics and 15 self-report questions about various symptoms including fatigue, concentration, dual tasking, bladder and bowel control. Three-month prospective diaries recorded falls.     RESULTS: There were 791 falls reported over the 3-month period from a total of 56 fallers. Falls rate per person-year was 32.08 falls. Following multivariable regression analysis, the model with the greatest levels of clinical utility and discriminative ability (sensitivity 88% and area under the receiving operating curve statistic = 0.72, 95% CI 0.62-0.82), included the variables of history of a fall, not having visual problems, problems with bladder control and a slower speed on the Timed Up and Go.     CONCLUSION: This study confirms the high incidence of falls for people with Multiple Sclerosis and provides a risk prediction model including fall history, problems with bladder control, not having visual problems and a slower Timed Up and Go speed that may be used to identify those at greater risk and in need of tailored falls prevention intervention.<p />  <p>Language: en</p>
LA  - en
SN  - 0269-2155
UR  - http://dx.doi.org/10.1177/0269215520973197
ID  - ref1
ER  -