TY  - JOUR
PY  - 2020//
TI  - Neurobiological effects of childhood abuse and neglect as a predisposing factor to substance use disorder
JO  - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
A1  - Katan, E. A.
SP  - 141
EP  - 147
VL  - 120
IS  - 11
N2  - The article presents data from research literature on the neurobiological consequences of abuse and neglect in childhood. It is shown that early life stress affects the trajectory of brain development, changes the patterns of cognitive behavioral control and reception of rewards, potentially increasing the risk of substance misuse. The combination of this factor with an immature prefrontal cortex can dramatically increase the liability to the development of substance dependence.<p />  <p>Language: ru</p>
LA  - ru
SN  - 1997-7298
UR  - http://dx.doi.org/10.17116/jnevro2020120111141
ID  - ref1
ER  -