TY - JOUR
PY - 2021//
TI - Evolution of irritability, anger, and aggression after traumatic brain injury: identifying and predicting subgroups
JO - Journal of neurotrauma
A1 - Miles, Shannon
A1 - Hammond, Flora McConnell
A1 - Neumann, Dawn
A1 - Silva, Marc A.
A1 - Tang, Xinyu
A1 - Kajankova, Maria
A1 - Dillahunt-Aspillaga, Christina
A1 - Nakase-Richardson, Risa
SP - ePub
EP - ePub
VL - ePub
IS - ePub
N2 - The current prospective, multi-center, longitudinal cohort study examined how Veterans/Service Members (V/SM) changed in their irritability, anger, and aggression (IAA) scores from admission to discharge in post-acute rehabilitation settings. The goals were to identify trajectory subgroups, and explore if there were different predictors of the subgroups. V/SM (N=346) from 5 Veterans Affairs TBI Model Systems Polytrauma Rehabilitation Centers participated. The sample was mostly men (92%) and identified as White (69%) Black (13%), and other races (18%). Median age was 28 years, and 78% sustained a severe TBI. Staff rated IAA at admission and discharge using the Mayo-Portland Adaptability Inventory-4 item#15. Four IAA trajectory subgroups were identified: 1.) No IAA at admission or discharge (n=89, 25.72%), 2.) Resolved IAA (n=61, 17.63%), 3.) Delayed Onset IAA (n=31, 8.96%), 4.) Persistent IAA (n=165; 47.69%). Greater posttraumatic stress disorder (PTSD) symptoms were the only consistent predictor of belonging to all the subgroups who had IAA compared to the No IAA subgroup. We conclude, IAA had different trajectories after a TBI. The majority of V/SM had persistent impairment from IAA, a quarter of the sample had no impairment from IAA, followed by IAA resolving, or getting worse.
FINDINGS emphasize the importance of educating providers and family of the different ways and times IAA can manifest after TBI. Timely diagnosis and treatment of PTSD symptoms during and after rehabilitation are critical treatment targets. Language: en
LA - en
SN - 0897-7151
UR - http://dx.doi.org/10.1089/neu.2020.7451
ID - ref1
ER -