TY  - JOUR
PY  - 2021//
TI  - Trajectories of suicidal ideation after first-episode psychosis: a growth mixture modeling approach
JO  - Acta psychiatrica Scandinavica
A1  - Salagre, Estela
A1  - Grande, Iria
A1  - Jiménez, Esther
A1  - Mezquida, Gisela
A1  - Cuesta, Manuel J.
A1  - Llorente, Cloe
A1  - Amoretti, Sílvia
A1  - Lobo, António
A1  - Gonzalez-Pinto, Ana
A1  - Carballo, Juan José
A1  - Corripio, Iluminada
A1  - Verdolini, Norma
A1  - Castro-Fornieles, Josefina
A1  - Legido, Teresa
A1  - Carvalho, André F.
A1  - Vieta, Eduard
A1  - Bernardo, Miquel
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - OBJECTIVE: The period immediately after the onset of first-episode psychosis (FEP) may present with high-risk for suicidal ideation (SI) and attempts, although this risk may differ among patients. Thus, we aimed to identify trajectories of SI in a 2-years follow-up FEP cohort and to assess baseline predictors and clinical/functional evolution for each trajectory of SI. <br><br>METHODS: We included 334 FEP participants with data on SI. Growth mixture modeling was used to identify trajectories of SI. Putative sociodemographic, clinical and cognitive predictors of the distinct trajectories were examined using multinomial logistic regression. <br><br>RESULTS: We identified three distinct trajectories: Non-SI trajectory (85.53% sample), Improving SI trajectory (9.58%) and Worsening SI trajectory (6.89%). Multinomial logistic regression model revealed that greater baseline pessimistic thoughts, anhedonia, and worse perceived family environment were associated with higher baseline SI followed by an Improving trajectory. Older age, longer duration of untreated psychosis, and reduced sleep predicted Worsening SI trajectory. Regarding clinical/functional evolution, individuals within the Improving SI trajectory displayed moderate depression at baseline which ameliorated during the study period, while the Worsening SI subgroup exhibited persistent mild depressive symptoms and greater functional impairment at follow-up assessments. <br><br>CONCLUSION: Our findings delineated three distinct trajectories of SI among participants with FEP, one experiencing no SI, another in which SI might depend on acute depressive symptomatology and a last subset where SI might be associated with mild but persistent clinical and functional impairments. These data provide insights for the early identification and tailored treatment of suicide in this at-risk population.<p />  <p>Language: en</p>
LA  - en
SN  - 0001-690X
UR  - http://dx.doi.org/10.1111/acps.13279
ID  - ref1
ER  -