TY  - JOUR
PY  - 2021//
TI  - Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson's disease
JO  - European journal of neuroscience
A1  - Moraca, Gabriel Antonio Gazziero
A1  - Beretta, Victor Spiandor
A1  - dos Santos, Paulo Cezar Rocha
A1  - Nóbrega-Sousa, Priscila
A1  - Orcioli-Silva, Diego
A1  - Vitório, Rodrigo
A1  - Gobbi, Lilian Teresa Bucken
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Falls are associated with impairment in postural control in people with Parkinson's disease (PwPD). We aimed to predict the fall risk through models combining postural responses with clinical and cognitive measures. Also, we compared the center of pressure (CoP) between PwPD fallers and non-fallers after unpredictable external perturbations. We expected that CoP parameters combined with clinical and cognitive measures would predict fall risk. Seventy-five individuals participated in the study. CoP parameters were measured during postural responses through 5 trials with unpredictable translations of the support-surface in posterior direction. Range and peak of CoP were analyzed in two periods: early and late responses. Time to peak (negative peak) and recovery time were analyzed regardless of the periods. Models included the CoP parameters in early (model 1), late responses (model 2), and temporal parameters (model 3). Clinical and cognitive measures were entered into all models. Twenty-nine participants fell at least once, and 46 PwPD did not fall during 12 months following the postural assessment. Range of CoP in late responses was associated with fall risk (p=0.046). However, although statistically non-significant, this parameter indicated low accuracy in predicting fall risk (area under the curve=0.58). Fallers presented a higher range of CoP in early responses than non-fallers (p=0.033). In conclusion, although an association was observed between fall risk and range of CoP in late responses, this parameter indicated low accuracy in predicting fall risk in PwPD. Also, fallers demonstrate worse postural control during early responses after external perturbations than non-fallers, measured by CoP parameters.<p />  <p>Language: en</p>
LA  - en
SN  - 0953-816X
UR  - http://dx.doi.org/10.1111/ejn.15143
ID  - ref1
ER  -