TY - JOUR PY - 2021// TI - The syndemic effects of mental ill health, household hunger, and intimate partner violence on adherence to antiretroviral therapy among pregnant women living with HIV in Yaoundé, Cameroon JO - PLoS one A1 - Cordoba, Evette A1 - Parcesepe, Angela M. A1 - Gallis, John A. A1 - Headley, Jennifer A1 - Soffo, Claudian A1 - Tchatchou, Berenger A1 - Hembling, John A1 - Baumgartner, Joy Noel SP - e0246467 EP - e0246467 VL - 16 IS - 2 N2 - BACKGROUND: This research advances understanding of interrelationships among three barriers to adherence to antiretroviral therapy (ART) among pregnant women living with HIV (WLWH) in Cameroon: probable common mental disorders (CMD), intimate partner violence (IPV), and hunger.

METHODS: The sample included 220 pregnant WLWH in Cameroon. Multivariable modified Poisson regression was conducted to assess the relationship between IPV, hunger, and CMD on ART adherence.

RESULTS: Almost half (44%) of participants recently missed/mistimed an ART dose. Probable CMD was associated with greater risk of missed/mistimed ART dose (aRR 1.5 [95% CI 1.1, 1.9]). Hunger was associated with greater risk of missed/mistimed ART dose among those who reported IPV (aRR 1.9 [95% CI 1.2, 2.8]), but not among those who did not (aRR 0.8 [95% CI 0.2, 2.3]).

CONCLUSION: Suboptimal ART adherence, CMD, and IPV were common among pregnant WLWH in Cameroon. Pregnant WLWH experiencing IPV and hunger may be especially vulnerable to suboptimal ART adherence.

Language: en

LA - en SN - 1932-6203 UR - http://dx.doi.org/10.1371/journal.pone.0246467 ID - ref1 ER -