TY  - JOUR
PY  - 2021//
TI  - An eeg signature of suicidal behavior in female patients with major depressive disorder? A non-replication
JO  - Biological psychology
A1  - Krepel, Noralie
A1  - Benschop, Lars
A1  - Baeken, Chris
A1  - Sack, Alexander T.
A1  - Arns, Martijn
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - INTRODUCTION: A recent study showed hypoactivity in the beta/gamma band in female suicide ideators and suicide attempters diagnosed with depression, relative to a low-risk group. The current study aimed to conceptually replicate these results. <br><br>METHODS: In the iSPOT-D sample (n = 402), suicide ideators and low-risk individuals were identified. Confining analyses to females only, differences between low-risk individuals and suicide ideators were tested for using the electroencephalogram (EEG) frequency bands SMR (Sensori-Motor-Rhythm; 12-15 Hz), beta (14.5-30 Hz), beta I (14.5-20 Hz), beta II (20-25 Hz), beta III (25-30 Hz), gamma I (31-49 Hz) using LORETA-software. <br><br>RESULTS: None of the tested frequency bands showed to be significantly different between suicide ideators and low-risk individuals. <br><br>CONCLUSIONS: The current study could not conceptually replicate the earlier published results. Several reasons could explain this non-replication, among which possible electromyographic (EMG) contamination in the beta/gamma band in the original study.     TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT00693849 URL: http://clinicaltrials.gov/ct2/show/NCT00693849.<p />  <p>Language: en</p>
LA  - en
SN  - 0301-0511
UR  - http://dx.doi.org/10.1016/j.biopsycho.2021.108058
ID  - ref1
ER  -