TY - JOUR PY - 2007// TI - Impulsivity and bipolar disorder JO - European Neuropsychopharmacology A1 - Najt, Pablo A1 - Perez, Jorge A1 - Sanches, M. A1 - Peluso, M. A. M. A1 - Glahn, D. A1 - Soares, Jair C. SP - 313 EP - 320 VL - 17 IS - 5 N2 - Impulsivity is frequently associated with bipolar disorder (BD) during manic episodes, but may also be present in euthymic bipolar patients. Aggression is an impulsivity-related behavior also found during manic episodes. The objective of this review is to further clarify the relationship between impulsivity and BD. A search in Medline and Psycinfo databases, combined with a manual search of selected references, was conducted to identify available literature on BD and impulsivity-related features. Although few studies have directly measured impulsivity in BD, available findings suggest that impulsivity is not only state-related, but also a trait component of BD, which could represent a core feature of the illness. Further research exploring the neurobiology of the impulsivity/BD relationship may contribute to elucidate the pathophysiology and to improve the diagnosis and treatment of this severe illness.

Language: en

LA - en SN - 0924-977X UR - http://dx.doi.org/10.1016/j.euroneuro.2006.10.002 ID - ref1 ER -