TY  - JOUR
PY  - 2021//
TI  - Rage and aggressive behaviour in frontal lobe epilepsy: description of a case and review of the mechanisms of aggressive behaviour in epilepsy and dementia
JO  - Epileptic disorders
A1  - Di Giacomo, Roberta
A1  - Didato, Giuseppe
A1  - Belcastro, Vincenzo
A1  - Deleo, Francesco
A1  - Pastori, Chiara
A1  - Arnaldi, Dario
A1  - Rosa, Giuseppa Jolanda
A1  - Villani, Flavio
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - The study of dementia and epilepsy may provide particular insight into behavioural alterations. We describe a rare case of ictal aggressive behaviour in a patient with focal epilepsy associated with a non-dominant dorso-lateral prefrontal lesion. During focal seizures, our patient showed intense agitation and anger, for a long time misinterpreted as psychogenic attacks, which disappeared after epilepsy surgery. The defined anatomical origin of such ictal emotional behaviour is not fully understood, however, the dorso-lateral prefrontal area appears to correlate less frequently with aggressiveness compared to the antero-mesial area. We describe the electroclinical data of our patient and provide a brief review of the mechanisms underlying aggressive conduct in epilepsy and dementia. An understanding of this mechanism could help to clarify the neural basis and treatment of violence associated with these and other neurological disorders. [Published with video sequence].<p />  <p>Language: en</p>
LA  - en
SN  - 1294-9361
UR  - http://dx.doi.org/10.1684/epd.2021.1277
ID  - ref1
ER  -