TY  - JOUR
PY  - 2021//
TI  - Psychosis and Dandy-Walker syndrome: a case report and review of the literature
JO  - General psychiatry
A1  - Porras Segovia, Alejandro
A1  - Guerrero-Jiménez, Margarita
A1  - Carrillo de Albornoz Calahorro, Carmen Maura
A1  - Gutiérrez-Rojas, Luis
SP  - e100254
EP  - e100254
VL  - 34
IS  - 2
N2  - Dandy-Walker syndrome (DWS) is a group of brain malformations which sometimes present with psychotic symptoms. We present the case of a patient diagnosed with Dandy-Walker variant who presented with schizophrenia-like psychosis. A man in his 30s was admitted to an acute psychiatric unit presenting with persecutory delusions, auditory hallucinations and violent behaviour. The MRI performed showed the typical alterations of Dandy-Walker variant: vermian hypoplasia and cystic dilatation of the fourth ventricle. He also suffered from mild intellectual disability. After being treated with olanzapine 10 mg/d for a month, his psychotic symptoms greatly improved and he was discharged. In conclusion, DWS may cause psychosis through a dysfunction in the circuit connecting prefrontal, thalamic and cerebellar areas. The association between these two conditions may contribute to the understanding of the aetiopathogenesis of schizophrenia.<p />  <p>Language: en</p>
LA  - en
SN  - 2517-729X
UR  - http://dx.doi.org/10.1136/gpsych-2020-100254
ID  - ref1
ER  -