TY  - JOUR
PY  - 2021//
TI  - Animal models of post-traumatic epilepsy and their neurobehavioral comorbidities
JO  - Seizure
A1  - Santana-Gomez, Cesar E.
A1  - Medel-Matus, Jesús Servando
A1  - Rundle, Brian K.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Traumatic brain injury (TBI) is defined as a disturbance in brain functioning caused by an external force. The development of post traumatic epilepsy (PTE) is a serious risk associated with TBI. Indeed, other neurological impairments are also common following TBI. In this review, we analyze and discuss the most widely used and best validated rodent models of TBI, with a particular focus on their contribution to the understanding of the PTE development. Furthermore, we explore the importance of these models for the study of other neurobehavioral comorbidities associated with brain injury. The efficient and accurate diagnosis of epilepsy and other neurological comorbidities as a consequence of brain trauma should improve the survival and quality of life of patients after TBI.<p />  <p>Language: en</p>
LA  - en
SN  - 1059-1311
UR  - http://dx.doi.org/10.1016/j.seizure.2021.05.008
ID  - ref1
ER  -