TY - JOUR PY - 2021// TI - Individual prediction of motor vehicle accidents for patients with epilepsy JO - Epilepsy and behavior A1 - Lin, Mintao A1 - Chen, Jiani A1 - Li, Sisi A1 - Qin, Yingjie A1 - Wang, Xuruan A1 - Liu, Yadong A1 - Zhang, Qi A1 - Taha Abdullah Abdulaziz, Ammar A1 - Zhou, Dong A1 - Li, Jinmei SP - 108046 EP - 108046 VL - 121 IS - Pt A N2 - The objective of the study was to design a clinically useful tool to predict the risk of seizure-related motor vehicle accidents (MVAs) for people with epilepsy (PWE). Participants were patients who visited our epilepsy center in West China Hospital from October 2012 to October 2019 and were divided into a primary cohort and a validation cohort. Ultimately, we included 525 patients in the primary cohort and 86 patients in the validation cohort. Proportional hazard regression was performed to measure the prognostic factors of car accidents. The outcome was used to create a nomogram model. The final model had 7 factors, with a C-index of 0.85 (95% CI, 0.80-0.91), to predict the possibility of non-MVA for PWE. For the validation cohort, the C-index was 0.83 (95% CI, 0.72-0.95). This nomogram model can offer more individualized advice to PWE who are still driving by estimating the risk of car accidents.

Language: en

LA - en SN - 1525-5050 UR - http://dx.doi.org/10.1016/j.yebeh.2021.108046 ID - ref1 ER -