TY  - JOUR
PY  - 2021//
TI  - Suicide attempts, neurocognitive dysfunctions and clinical correlates in middle-aged and elderly Chinese schizophrenia patients
JO  - Frontiers in psychiatry
A1  - Huang, Yuanyuan
A1  - Wu, Kai
A1  - Jiang, Rui
A1  - Zeng, Xiaoying
A1  - Zhou, Sumiao
A1  - Guo, Weijian
A1  - Feng, Yangdong
A1  - Zou, Caimei
A1  - Li, Hehua
A1  - Li, Ting
A1  - Ning, Yuping
A1  - Yang, Mingzhe
A1  - Wu, Fengchun
SP  - 684653
EP  - 684653
VL  - 12
IS  - 
N2  - BACKGROUND: Suicide is a common and complex symptom of schizophrenia that may be related to clinical variables and neurocognitive function. This study aimed to investigate the associated correlates of suicide attempts in Chinese middle-aged and elderly inpatients with schizophrenia, including demographic and clinical characteristics and cognitive level, which has not yet been reported. <br><br>METHODS: A total of 426 schizophrenia inpatients were recruited for this study. Clinical symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS). Neurocognitive function was measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). <br><br>RESULTS: The prevalence of suicide attempts in middle-aged and elderly Chinese schizophrenia patients was 13.3%. Female patients had a higher suicide rate than male patients. Patients with suicide attempts had significantly higher PANSS-positive subscores, depressive subscores, and RBANS-story recall than non-attempter patients (all p < 0.05). Multiple logistic regression showed that gender, positive subscore, depressive subscore and RBANS-story recall (OR = 1.10-2.19, p < 0.05) were independently associated with suicide attempts in middle-aged and elderly schizophrenia patients. <br><br>CONCLUSIONS: Our study showed that the rate of suicide attempts in Chinese middle-aged and elderly schizophrenia patients is high. Compared to non-attempters, there are less cognitive impairments, more clinical symptoms, and more female patients in the suicide attempters.<p />  <p>Language: en</p>
LA  - en
SN  - 1664-0640
UR  - http://dx.doi.org/10.3389/fpsyt.2021.684653
ID  - ref1
ER  -