TY - JOUR PY - 2021// TI - Neuroimaging features in diethylene glycol poisoning JO - Arquivos de Neuro-Psiquiatria A1 - Silva Júnior, Cilmário Leite da A1 - Freitas, Leonardo Furtado A1 - Pereira, Mariana Leite A1 - Elias, Juliana Souza Silva A1 - Pedroso, José Luiz A1 - Marussi, Victor Hugo Rocha SP - ePub EP - ePub VL - ePub IS - ePub N2 - Diethylene glycol is a substance commonly used in industrial products including antifreeze and coolant. Its toxicity causes severe metabolic acidosis, coma and multiorgan failure1. Neurological toxicity is less well characterized, but brain MRI lesions may include cerebellar and thalamic abnormalities, with diffuse restriction. A 55-year-old man presented with acute onset vomiting, tetraplegia and ptosis, that progressed to renal failure and coma, four days after consuming beer. Several people that consumed that specific beer developed similar symptoms. Brain MRI showed restricted diffusion on cerebellum and thalamus. Beer analysis showed high levels of diethylene glycol. Patient died days later.
Language: en
LA - en SN - 0004-282X UR - http://dx.doi.org/10.1590/0004-282X-ANP-2020-0348 ID - ref1 ER -