TY  - JOUR
PY  - 1995//
TI  - Fatal intoxication with amlodipine
JO  - Journal of toxicology - clinical toxicology
A1  - Koch, A. R.
A1  - Vogelaers, D. P.
A1  - Decruyenaere, J. M.
A1  - Callens, B.
A1  - Verstraete, Alain Gaston
A1  - Buylaert, W. A.
SP  - 253
EP  - 256
VL  - 33
IS  - 3
N2  - Although poisoning with calcium channel blocking agents is frequent, to our knowledge no cases involving amlodipine have been published. We describe here a case of amlodipine intoxication, in which protracted hypotension did not respond to vasopressor therapy alone. After the addition of continuous calcium chloride and glucagon infusion, blood pressure was restored and vasopressor therapy could be tapered off substantially. When calcium and glucagon were interrupted because of severe hypercalcemia and hyperglycemia, the patient developed irreversible hypotension and died. Either glucagon or calcium or both, and to some extent vasopressors, seem to have constituted effective treatment of hypotension in this case.<p />  <p>Language: en</p>
LA  - en
SN  - 0731-3810
UR  - http://dx.doi.org/
ID  - ref1
ER  -