TY - JOUR PY - 2021// TI - Terror in Paris: incidence and risk factors for infections related to high-energy ammunition injuries JO - Anaesthesia, critical care and pain medicine A1 - Birnbaum, Ron A1 - Bitton, Rudy A1 - Pirracchio, Romain A1 - Feral-Pierssens, Anne-Laure A1 - Constant, Anne-Laure A1 - Dubost, Clément A1 - Chousterman, Benjamin A1 - Lescot, Thomas A1 - Lortat-Jacob, Brice A1 - Harrois, Anatole A1 - Abback, Paër-Sélim A1 - Belbachir, Anissa A1 - Basto, Emmanuel A1 - Castier, Yves A1 - Laitselart, Philippe A1 - Carli, Pierre A1 - Lapostolle, Frederic A1 - Tourtier, Jean Pierre A1 - Langlois, Matthieu A1 - Raux, Mathieu A1 - Mounier, Roman SP - ePub EP - ePub VL - ePub IS - ePub N2 - BACKGROUND: We aimed to assess the incidence and the risk factors for secondary wound infections associated to high-energy ammunition injuries (HEAI) in the cohort of civilian casualties from the 2015 terrorist attacks in Paris.

METHODS: This retrospective multi-centric study included casualties presenting at least one HEAI who underwent surgery during the first 48 hours following hospital admission. HEAI associated infection was defined as a wound infection occurring within the initial 30 days following trauma. Risk factors were assessed using univariate and multivariate analysis.

RESULTS: Among the 200 included victims, the rate of infected wounds was 11.5%. The median time between admission and the surgical revision for secondary wound infection was 11 days [9-20]. No patient died from an infectious cause. Infections were poly-microbial in 44 % of the cases. The major risk factors for secondary wound infection were ISS (p < 0.001), SAPS II (p < 0.001), MGAP (p < 0.001), haemorrhagic shock (p = 0.003), use of vasopressors (p < 0.001), blood transfusion (p < 0.001), abdominal penetrating trauma (p = 0.003), open fracture (p = 0.01), vascular injury (p = 0.001), duration of surgery (p = 0.009), presence of surgical material (p =  0.01). In the multivariate analysis, the SAPS II score (OR 1.07 [1.014-1.182], p = 0.019) and the duration of surgery (OR 1.005 [1.000-1.012], p = 0.041) were the only risk factors identified.

CONCLUSION: We report an 11.5% rate of secondary wound infection following high-energy ammunition injuries. Risk factors were an immediately severe condition and a prolonged surgery.

Language: en

LA - en SN - 2352-5568 UR - http://dx.doi.org/10.1016/j.accpm.2021.100908 ID - ref1 ER -