TY  - JOUR
PY  - 2021//
TI  - Childhood maltreatment and metabolic syndrome in bipolar disorders: in search of moderators
JO  - Psychoneuroendocrinology
A1  - Godin, Ophelia
A1  - Gaube, Géraud
A1  - Olié, Emilie
A1  - Belzeaux, Raoul
A1  - Bellivier, Frank
A1  - Loftus, Josephine
A1  - Courtet, Philippe
A1  - Dubertret, Caroline
A1  - Llorca, Pierre-Michel
A1  - Gard, Sebastien
A1  - Henry, Chantal
A1  - Schwan, Raymund
A1  - Passerieux, Christine
A1  - Polosan, Mircea
A1  - Samalin, Ludovic
A1  - Leboyer, Marion
A1  - Etain, Bruno
SP  - 105327
EP  - 105327
VL  - 131
IS  - 
N2  - As compared to the general population, adult individuals with bipolar disorders (BD) have higher mortality rates due to cardiovascular diseases and higher prevalence of Metabolic Syndrome (MetS). Recent evidence suggests that childhood maltreatment may contribute to the cardiovascular burden in individuals with BD. However, studies are scarce, with limited sample sizes and inconsistent results. We explored the associations between a self-reported history of childhood maltreatment and MetS (and its subcomponents) in a large sample of 2390 individuals with BD. Childhood maltreatment was assessed using the Childhood Trauma Questionnaire and MetS was defined according to the revised criteria of the ATEP III. We suggested associations between childhood maltreatment and the presence of MetS in men and in younger individuals. The association between childhood maltreatment and the presence of MetS in the early onset subgroup was not significant after adjustment for site of recruitment and level of education. Hence, some links between childhood maltreatment and MetS might exist only in specific subgroups of individuals with BD, but confirmation is required in independent and large samples, while taking into account potential confounders. This would help defining how psychosocial interventions that target childhood maltreatment and its consequences may be beneficial for physical health.<p />  <p>Language: en</p>
LA  - en
SN  - 0306-4530
UR  - http://dx.doi.org/10.1016/j.psyneuen.2021.105327
ID  - ref1
ER  -