TY  - JOUR
PY  - 2021//
TI  - The Stockholm Spinal Cord Uro Study: 3. urodynamic characteristics in a regional prevalence group of persons with spinal cord injury and indications for improved follow-up
JO  - Scandinavian journal of urology
A1  - Farrelly, Elisabeth
A1  - Lindbo, Lena
A1  - Seiger, Åke
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - AIMS: Examine the outcome of urodynamic studies in a regional prevalence group of patients with traumatic spinal cord injury (SCI), explore relationships between urodynamic parameters and renal complications/other SCI-related dysfunctions, assess the role of urodynamics in SCI follow-up. <br><br>METHODS: In a cross-sectional study, 211 patients were included, who attended a yearly check-up and had urodynamics performed as part of the follow-up in addition to S-creatinine, S-cystatin-C, renal ultrasound, and a questionnaire regarding complications. Relationships between urodynamic parameters and renal complications/other SCI-related dysfunctions were explored by descriptive and comparative statistics. <br><br>RESULTS: Neurogenic detrusor overactivity (NDO) was found in 150, underactive/acontractile detrusor in 44, normal detrusor function in 17 patients. Maximum detrusor pressures during filling/voiding in NDO attained mean levels of >40 cm H(2)O in 68% of patients and >25 cm H(2)O in 83%. Reduced compliance of the bladder wall, cystometric bladder capacity <250 mL, and detrusor overactivity leakage during filling were associated with higher detrusor pressures. Detrusor overactivity during more than one-third of the filling phase was significantly related to signs of renal complications among patients with SCI duration 11-20 years. No significant relationships were found between other urodynamic parameters and renal/other SCI-related complications. Renal complications in underactive/acontractile and normal detrusor function co-varied with evidence of previous NDO and other co-morbidities which may negatively influence kidney function. <br><br>CONCLUSIONS: Maximum detrusor pressures during the filling/voiding phases attained high levels in a majority of patients. Detrusor overactivity during more than one-third of the filling phase was significantly related to signs of renal complications.<p />  <p>Language: en</p>
LA  - en
SN  - 2168-1805
UR  - http://dx.doi.org/10.1080/21681805.2021.1954994
ID  - ref1
ER  -