TY  - JOUR
PY  - 2021//
TI  - The interactions between childhood adversities and recent stress were associated with early-adulthood depression among Chinese undergraduate students
JO  - Depression and anxiety
A1  - Li, Xiaojing
A1  - Guo, Wanjun
A1  - Tang, Wanjie
A1  - Lv, Qiuyue
A1  - Zhang, Yamin
A1  - Yu, Hua
A1  - Wang, Qiang
A1  - Deng, Wei
A1  - Zhao, Liansheng
A1  - Ma, Xiaohong
A1  - Meng, Yajing
A1  - Li, Mingli
A1  - Wang, Huiyao
A1  - Chen, Ting
A1  - Liu, Yan-Song
A1  - Tang, Zhen
A1  - Du, Xiang-Dong
A1  - Greenshaw, Andrew J.
A1  - Li, Tao
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - BACKGROUND: It is widely acknowledged that childhood adversities (CAs) and recent stress are potential risk factors for adult depression. However, the mechanism(s) by which interactions of CAs with recent stress affect adult depression remain unclear. AIMS: To investigate the predictive association of the interaction among CAs and recent stress with early-adult depression. <br><br>METHOD: We conducted an annual survey of all freshmen for the period of 2016-2018 in a Chinese comprehensive university, with a sample size of 23,206. An online questionnaire including standardized self-report instruments was used to assess sociodemographic factors, childhood experiences of left-behind (CELB), and maltreatments (CEMTs) including beating (CEB), neglect (CEN), sexual abuse (CESA), recent stress, and current depression (measured by the 9-item Patient Health Questionnaire). <br><br>RESULTS: The correlation of Individual CAs and recent stress was significant. In addition to their significant independent/direct incremental effects, all surveyed CAs were associated with increased severity of early-adult depression, and increased frequency of clinically significant depression (CSD), through significant associations with recent stress (mediation effect). History of CEMTs including CEB, CEN, and CESA significantly increased the effects of recent stress on depression (moderation effect). <br><br>CONCLUSIONS: Chinese undergraduate students reported frequent history of exposure to CAs, which increased the likelihood of depression in early adulthood, not only directly but also through the increasing the likelihood (mediation effect) and impact (moderation effect) of recent stress on depression. These novel findings may help to extend our understanding of environmental determinants of depression, and to guide further research, clinical practice, and policy in this context.<p />  <p>Language: en</p>
LA  - en
SN  - 1091-4269
UR  - http://dx.doi.org/10.1002/da.23201
ID  - ref1
ER  -