TY  - JOUR
PY  - 2021//
TI  - Sleep inertia measurement with the psychomotor vigilance task in idiopathic hypersomnia
JO  - Sleep
A1  - Evangelista, Elisa
A1  - Rassu, Anna Laura
A1  - Lopez, Regis
A1  - Biagioli, Niccolò
A1  - Chenini, Sofiene
A1  - Barateau, Lucie
A1  - Jaussent, Isabelle
A1  - Dauvilliers, Yves
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - STUDY OBJECTIVES: Sleep inertia is a frequent and disabling symptom in idiopathic hypersomnia (IH), but poorly defined and without objective measures. The study objective was to determine whether the psychomotor vigilance task (PVT) can reliably measure sleep inertia in patients with IH or other sleep disorders (non-IH). <br><br>METHODS: Sixty-two (51 women, mean age: 27.7±9.2) patients with IH and 140 (71 women, age: 33.3±12.1) with non-IH (narcolepsy=29, non-specified hypersomnolence NSH=47, obstructive sleep apnea=39, insomnia=25) were included. Sleep inertia and sleep drunkenness in the last month (M-sleep inertia) and on PVT day (D-sleep inertia) were assessed with three items of the Idiopathic Hypersomnia Severity Scale (IHSS), in drug-free conditions. The PVT was performed four times (7:00 PM, and 7:00, 7:30 and 11:00 AM) and three metrics were used: lapses, mean 1/Reaction Time (RT), slowest 10% 1/RT. <br><br>RESULTS: Sleep inertia was more frequent in patients with IH than non-IH (56.5% and 43.6% with severe sleep inertia in the past month, including 24% and 12% with sleep drunkenness). Lapse number increase and slowest 10% 1/RT decrease, particularly at 7:00 and 7:30AM, were proportional with M-sleep inertia severity, but regardless of sleep drunkenness and sleep disorders. Similar results were obtained when PVT results were compared in patients with/without D-sleep inertia, with the largest increase of the lapse number at 7:00 and 7:30AM associated with severe sleep inertia and sleep drunkenness. <br><br>CONCLUSION: PVT is a reliable and objective measure of sleep inertia that might be useful for its characterization, management and follow-up in patients with IH.<p />  <p>Language: en</p>
LA  - en
SN  - 0161-8105
UR  - http://dx.doi.org/10.1093/sleep/zsab220
ID  - ref1
ER  -