TY  - JOUR
PY  - 2021//
TI  - Advancing a temporal framework for understanding the biology of nonsuicidal self- injury: an expert review
JO  - Neuroscience and biobehavioral reviews
A1  - Kaess, Michael
A1  - Hooley, Jill M.
A1  - Klimes-Dougan, Bonnie
A1  - Koenig, Julian
A1  - Plener, Paul L.
A1  - Reichl, Corinna
A1  - Robinson, Kealagh
A1  - Schmahl, Christian
A1  - Sicorello, Maurizio
A1  - Schreiner, Mindy Westlund
A1  - Cullen, Kathryn R.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Nonsuicidal self-injury (NSSI) is a serious clinical problem, particularly for adolescents and young adults. NSSI is a complex behavior that emerges through the intersecting effects of social, psychological, and biological mechanisms. Although the social and psychological contributions to risk for developing NSSI are relatively well understood and have guided the development of effective psychosocial treatments for self-injury, the biological mechanisms underlying NSSI have just begun to come to light. To evaluate and categorize the biological research conducted on the topic of NSSI, we propose a model that distinguishes between trait and state markers. According to this model, risk factors and mechanisms involved in NSSI can be distinguished into both trait and state factors. We review the existing evidence on distal biological traits (predictors) of NSSI, proximal biological traits (correlates) of NSSI, and biological states directly preceding or following NSSI. We conclude by providing recommendations for future research on the neurobiology of NSSI.<p />  <p>Language: en</p>
LA  - en
SN  - 0149-7634
UR  - http://dx.doi.org/10.1016/j.neubiorev.2021.08.022
ID  - ref1
ER  -