TY  - JOUR
PY  - 2021//
TI  - Sports related brain injury and neurodegeneration in athletes
JO  - Current molecular pharmacology
A1  - Dhote, Vipin V.
A1  - Raja, Muthu Kumaradoss Mohan Maruga
A1  - Samundre, Prem
A1  - Sharma, Supriya
A1  - Anwikar, Shraddha
A1  - Upaganlawar, Aman B.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Sports deserve a special place in human life to impart healthy and refreshing wellbeing. However, sports activities, especially contact sports, renders athlete vulnerable to brain injuries. Athletes participating in a contact sport like boxing, rugby, American football, wrestling, and basketball are exposed to traumatic brain injuries (TBI) or concussions. The acute and chronic nature of these heterogeneous injuries provides a spectrum of dysfunctions that alters the neuronal, musculoskeletal, and behavioral responses of an athlete. Many sports-related brain injuries go unreported, but these head impacts trigger neurometabolic disruptions that contribute to long-term neuronal impairment. The pathophysiology of post-concussion and its underlying mechanisms are undergoing intense research. It also shed light on chronic disorders like Parkinson's disease, Alzheimer's disease, and dementia. In this review, we examined post-concussion neurobehavioral changes, tools for early detection of signs, and their impact on the athlete. Further, we discussed the role of nutritional supplements in ameliorating neuropsychiatric diseases in athletes.<p />  <p>Language: en</p>
LA  - en
SN  - 1874-4672
UR  - http://dx.doi.org/10.2174/1874467214666210910114324
ID  - ref1
ER  -